Effect of Selenium and Vitamin E Injection during Late Pregnancy on Immune System and Productive Performances of Sanjabi Ewes and Their Lambs

mohammad moeini

Abstract


This study was preformed to investigate the effect of selenium and vitamin E supplementation during late pregnancy on plasma and colostrum selenium concentrations and immune system of Sanjabi ewes and their lambs. Twenty seven Sanjabi ewes were randomly assigned to three treatments groups. Four and two weeks before expected lambing, ewes were injected intramuscularly 0 ml (C) 5 ml (T1), 10 ml (T2) selenium and vitamin E respectively. Each ml of the supplement containing of 0.5 mg Se as sodium selenite and 50 mg vitamin E as D, L-alpha-tocopheryl acetate. Plasma and colostrum Se concentrations, colostrum and plasma IgG concentrations, white blood cell and differential leukocyte counts were measured. The results showed that plasma Se concentrations were significantly increased in T2 compared with controls as well as plasma Se concentration of lambs of treatments were significantly increased compared with lambs of control. The colostrum Se concentrations were significantly increased in Se supplemented groups compared with control. White blood cell counts was higher in lambs of T2 when compared with controls (P<0.05). The colostrum IgG concentrations at one hour postpartum were higher in T2 compared with controls (P<0.05). The mean colostrum production at one hour  postpartum did not differ between ewes but the mean colostrum production at 10 and 18 hours postpartum increased in ewes of T2 group (P<0.05). The length of restless prepartum and length of gestation in supplemented ewes were shorter than controls. In conclusion, selenium and vitamin E injection during late pregnancy at the level of 10 ml could have influenced passive immune system and ewes and  lambs performance.


Keywords


Selenium;White blood cell;Immunoglobulin G; Colostrum;production;Sheep

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References


Abd El-Ghany, H. and J.L. Tortora-Perez. 2010. The importance of selenium and the effects of its deficiency in animal health. Small Rumin. Res. 89:185-192.

Abdelrahman, M.M. and R.L. Kincaid. 1995. Effect of selenium supplementation of cows on maternal transfer of selenium to fetal and newborn calves. J. Dairy Sci. 78: 625-630.

Ammerman, C.B.L., G.W. Chapman, J.P. Bouwman, C.P. Fontenot, Bagley and A.L. Moxon. 1980. Effect of supplemental selenium for beef cows on the performance and tissue selenium concentrations of cows and suckling calves. J. Anim Sci. 51:1381-1386.

Andres, S., M.C. Mane, and J. Sanchez. 1996. Changes in GSHPx and muscle enzyme activities in lambs with nutritional myodegeneration following a single treatment with sodium selenite. Small Rumin Res. 23:183–186.

Boland,T. M., N. Keane, P. Nowakowski, P.O. Brophy and T.F. Crosby. 2005. High mineral and vitamin E intake by pregnant ewes lowers colostral immunoglobulin G absorption by the lamb. J. Anim Sci. 83,871–878.

Bourne, N., D.C. Wathes, K.E. Lawrence, M. McGowan and R.A. Laven 2007. The effect of parenteral supplementation of vitamin E with selenium on the health and productivity of dairy cattle in the UK. Vet. J. 10: 10–16.

Cay, M., and M. Naziroglu, 1999. Effects of intraperitoneally-administered vitamin E and selenium on the blood biochemical and haematological parameters in rats. Cell Biochem. Funct. 17: 143–148.

Chen, C.Y., and T.H. Lin. 2000. Effects of selenium dioxide on blood and femoral bone marrow of rats. J. Toxicol. Envir. Health. 59: 553–560.

Christaldi, L.A.L., C.D. Mc Dowel, P.A. Buergelt, N.S. Davis and F.G. Wilkinson Martin. 2005. Tolerance of inorganic selenium in wether sheep. Small Rumin. Res. 56: 205- 213.

Davis, P. A., L.R. McDowell, C.D. Wilkinson, A. Buergelt, R.N. Van Alstyne, T.T. Weldon Marshall. 2006. Effects of selenium levels in ewes diet on selenium in milk and the plasma and tissue selenium concentrations of lambs. Small Rum. Res. 65: 14-23.

Dominguez-Vara, I.A., S.S. Gonzalez-Munoz, J.M. Pinos-Rodriguez, J.L. Borquez Gastelum, R. Barcena-Gama, G. Mendoza-Martinez, L.E. Zapata and L.L. Landois-Palencia. 2009. Effects of feeding selenium-yeast and chromium-yeast to finishing lambs on growth, carcass characteristics, and blood hormones and metabolites. Anim. Feed Sci. Technol.152:42-49.

Enjalbert, F., P. Lebreton, O. Salat and F. Schelcher. 1999. Effect of pre or post partum selenium supplementation on selenium status in beef cows and their calves. J. Anim. Sci. 77:223-229.

Faixova, Z., S. Faix, L. Leng, P. Vaczi, Z. Makova, R. Szaboova. 2007. Haematological, blood and rumen chemistry changes in lambs following supplementation with Se-yeast. Acta Vet. 76:3–8.

Fazaeli, H., and A.R. Talebian-Masoudy. 2009. Effect of Selenium and Vitamin E Supplement on the performance of sheep in central Iran. FAO/IAEA International Symposium on Sustainable Improvement of Animal Production and Health. 8–11 June 2009 Synopses Vienna, Austria, 45–46.

Florence, T. M. 1995. The role of free radicals in disease. Aus.t NZJ. Ophthalmol. 23 (1):3-7

Gabryszuk, M., and J. Klewiec. 2002. Effect of injecting 2- and 3-year-old ewes with selenium and selenium–vitamin E on reproduction and rearing of lambs. Small Rum. Res. 43( 2): 127–132.

Givens, D. I., R. Allison, B. Cottrill and J.S Blake 2004. Enhancing the selenium content of bovine milk through alteration of the form and concentration of selenium in the diet of the dairy cow. J. Sci. food Agric. 84:811-817.

Hu, M.L., C. Chung and J.E. Spallholz. 1984. Heamatologic data of selenium – deficient and selenium supplemented rats. Journal Inorganic Biochemistry. 22: 165-173.

Izadyar, F. 1987. Serum creatin kinase and whole blood concentrations of clinically normal sheep of various regions of Iran. D.V.M. Thesis no 1709, School of Veterinary Medicine, Tehran University.

Jain, N.C. 1986. Schism’s veterinary hematology. Lea and Febiger, Philadelphia, pp 66–67

John R. C, 2009.The ELISA Guidebookâ€, Second Edition, ISBN: 978-1-60327-253-7, Humana Press, a part of Springer Science + Business Media, LLC 2009.

Jalilian, M.T. 2012. The effect of injection selenium and vitamin E supplementation on plasma Se, Cu, Fe and Zn status during the late pregnancy of Sanjabi ewes and their lambs. M.Sc Theses, Azad University, Saveh, Iran.

Jalilian, M.T., M.M. Moeini and K. Karkodi. 2012. Effect of selenium and vitamin E supplementation during late pregnancy on colostrum and plasma Se, Cu, Zn and Fe concentrations of fat tail Sanjabi ewes and their lambs. Acta Agriculturae Slovenica. 100(2): 125-129.

Juniper, D.T., R.H. Phipps, A.K. Jones and G. Bertin. 2006. Selenium supplementation of lactating dairy cows: effect on selenium concentration in blood, milk, urine and feces. Journal of Dairy Science. 89: 3544–3551.

Kachuee, R. 2011. The effect of dietary organic and inorganic selenium supplementation on serum Se, Cu, Fe and Zn status during the late pregnancy in Morghoz goats and their kids M.Sc Theses, Razi university, Kermanshah, Iran.

Kachuee, R., M.M. Moeini and M. Souri. 2013. The effect of dietary organic and inorganic selenium supplementation on serum Se, Cu, Fe and Zn status during the late pregnancy in Merghoz goats and their kids. Small Rum. Res. 110:20-27

Kehrli, J.R.M., B.J. Nonnecke, J.A. Roth. 1989. Alterations in Bovine neutrophil function during the peripartum period. Anim. J. Vet. Res. 50:207–214.

Kim, Y.Y., and D.C. Mahan. 2001. Prolonged feeding of high dietary levels of organic and organic selenium to gilt from 25 Kg Body weight through one parity. Anim. Sci. 79: 956-966

Kincaid, R.L., and M. Rock. 1999. Selenium for ruminants: comparing organic and inorganic selenium for cattle and sheep. Proceedings 15th Alltech Annual Symposium.

Knowles, S.o, N.D. Grace, K. Wurms and J. Lee. 1999. Significance of amount and form of dietary selenium on blood, milk and casein selenium concentrations in grazing cows. J. Dairy Sci. 82:429-437.

Koyuncu, M. and H. Yerlikaya. 2007. Effect of selenium-vitamin E injections of ewes on reproduction and growth of their lambs. South Afr. J. Anim. Sci. 37:233-236.

Kumar, M.A.K., R.S. Garg, V.K. Dass, V. Chaturvedi, V.P. Mudgal Varshney. 2009. Selenium supplementation influences growth performance, antioxidant status and immune response in lambs. Anim. Feed Sci. Tech. 153:77-87.

Lacetera, N., U. Bernabucci, B. Ronchi and A. Nardone. 1996. Effects of selenium and vitamin E administration during a late stage of pregnancy on colostrum and milk production in dairy cows and on passive immunity and growth of their offspring. Am. J. Vet. Res. 57:1776–1780.

Li, F.S., Y.J. Duan, S.J. Yan, , J.Y. Guan, L.M. Zou, F.C. Wei, L.Y. Mong and S.Y. LIL Li. 1990. Presenile (early ageing) changes in tissues of Kaschin-Beck disease and its pathogenic significance. Mech. Ageing Development. 54: 103-120.

Mahan, D. C. 2000. Effect of organic and inorganic selenium sources and levels on sow colostrums and milk selenium content. J. Anim Sci. 78. 100- 10.

McDowell, L.R. 2003. Minerals in Animal and Human Nutrition. 2nd, 644 pages. Elsevier Science B.V. Amsterdam, Netherlands.

Meschy, F. 2000. Recent progress in the assessment of mineral requirements of goats. Liv. Prod. Sci. 64: 9–14.

Meyer, A. M., J.J. Reed, T.L. Neville, J.F. Thorson, K.R. Maddock-Carlin, J.B. Taylor, L.P. Reynolds, , D.A. Redmer, J.S. Luther, C.J. Hammer, K.A. Vonnahme, J.S. Caton. 2011. composition of colostrum and milk in primiparous ewes Nutritional plane and selenium supply during gestation affect yield and nutrient. J. Anim. Sci. 89:1627-1639.

Moeini, M. M., H. Karami and E. Mikaeili. 2009. Effect of selenium and vitamin E supplementation during the late pregnancy on reproductive indices and milk production in heifers. J. Anim. Rep. Sci. 114: 109–114.

Moeini, M.M., A. Kiani, H. Karami and E. Mikaeili. 2011a. The Effect of Selenium Administration on the Selenium, Copper, Iron and Zinc Status of Pregnant Heifers and Their Newborn Calves. J. Agr. Sci. Tech. l (13): 53-59.

Moeini, M.M., A. Kiani, E. Mikaeili and H. Karami Shabankareh. 2011b. Effect of Prepartum Supplementation of Selenium and Vitamin E on Serum Se, IgG Concentrations and Colostrum of Heifers and on Hematology, Passive Immunity and Se Status of Their Offspring. Biol Trace Elem. Res. 144:529 – 537.

Mohri, M., H.A. Seiï¬ and J. Khodadi. 2005. Effects of pre-weaning parenteral supplementation of Vitamin E and selenium on hematology, serum proteins and weight gain in dairy calves. Comp. Clin. Pathol. 14: 149–154.

Munoz, C., A.F. Carson, M.A. McCoy, L.E.R. Dawson, N.E. Connell, A.W. Gordon. 2009. Effect of plane of nutrition of 1- and 2-year-old ewes in early and mid pregnancy on ewe reproduction and offspring performance up to weaning. Animal. 3:657-669.

National Research Council. 1985. Nutrient Requirements of Sheep. 6th ed. Natl. Acad. Press, Washington, DC.

Pisek L, J. Travnicek, J. Salat, V. Kroupova and M. Soch. 2008 Changes in white blood cells in sheep blood during selenium supplementation. Vet. Med. 53:255 – 259.

Rastogi, I. 2007. Essentials of Animal Physiology†4 edition, ISBN: 978-81-224-2429-4, New Age International (P) Ltd., Publishers.

Rock, M. J., R.L. Kincaid and G.E. Carstens. 2001. Effects of prenatal source and level of dietary selenium on passive immunity and thermo metabolism of newborn lambs. Small Rum. Res. 40:129-138.

Schultz RD, H.W. Dunne and C.E. Heist. 1973.Ontogeny of bovine immune response. Infection and Immunity. 7: 981–991.

Smith, K.L., J.S. Hogan and W.P. Weiss. 1997. Dietary vitamin E and selenium affect mastitis and milk quality. Anim. Sci. 75:1659–1665.

Sweeker, W.S., C.D. Thatcher, D.E. Eversole, D.J. Blodgett and G.G. Schurig. 1995. Effect of selenium supplementation on colostral IgG concentration in cows grazing selenium-deficient pastures on postsuckle serum IgG concentration in their calves. Am. J. Vet. Res. 56:450–453.

Taylor, J. B., L.P. Reynolds, D.A. Redmer, J.S. Caton. 2009. Maternal and fetal tissue sele-nium loads in nulliparous ewes fed supranutritional and excessive selenium during mid to latepregnancy. J. Anim. Sci. 87:1828–1834.

Tras, B., F. Inal, A.L. Bas, V. Altunok, M. Elmas and E. Yazar. 2000. Effect of continuous supplementations of ascorbic acid, aspirin, vitamin E and selenium on some hematological parameters and serum superoxidase dismutase levels in broiler chicken. Br. Poultry Sci. 41:664–666.

Underwood, E.J. and N.F. Suttle. 1999. Mineral nutrition of livestock. 3 rd ed. CAB Int., Wallingford, oxon, U.K.

Van Ryssen, J.B.J. , R.J. Coertze, M.F. Smith. 2012.Time-dependent effect of selenium supplementation on the relationship between selenium concentration in whole blood and plasma of sheep. Small Ruminant Res. http://dx.dot.org/10.1016/j.smallrumres.2012.10.008.

Weiss, W.P. 2003. Selenium nutrition of dairy cows: comparing responses to organic and inorganic selenium forms. In: Lyons, P.T., Jacques, K.A. (Eds.), Proc. 19th. Alltech. Annual. Symp., Nutritional Biotechnology in Feed and Food Industries. Nottingham University Press, Nottingham, pp: 333–343.


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